Science

Marijuana may not lower your IQ [while possibly enhancing your EQ?]

In Jackson and Iacono’s analysis, marijuana use and IQ were completely uncorrelated, and IQ measures fell equally in both the users and abstainers. Subsequent twin studies, including one performed with U.K. data by the Dunedin team, corroborated these findings of no relationship between marijuana use and a falling IQ. Next, investigators uncovered shared underlying vulnerability factors that explained…

READ MORE
Science

The psychedelic research hiatus and its relevance today

[In the 1950’s and 60’s] psychedelics were of little interest to pharmaceutical companies as the intervention seemed to treat illness, rather than alleviate symptoms. Consequently, the financial imperatives were lacking; fully recovered patients would not require continued medication… Sandoz was reluctant to share such proprietary and patented data (Bonson, 2018). When required by the FDA, the company…

READ MORE
Science

[Does synthetic psilocybin]… cause nausea?

Some participants in studies using pure, synthetic psilocybin report nausea as a side effect of their treatment. This points the finger at [synthetic] psilocybin as a possible cause of nausea… Also, because the body quickly converts psilocybin to its active form psilocin, this suggests that psilocin may play a role in nausea. Original Article (Psychedelic…

READ MORE
Science

Habitat influences psychoactive toad secretions

…human intervention further altered the habitat of the Amazon-Cerrado toads. One could hypothesize that this disturbance could not only affect the habitat, and thus the available food, but it may also put stress on the toads… This stress could conceivably cause them to produce different combinations and amounts of compounds in their secretions by way…

READ MORE
Science

Psychedelic compound from magic mushrooms produced in yeast

…production [of psilocybin] in bacteria [such as e-coli] comes with a wide range of concerns [some of which] can be addressed by using yeast instead. In yeast, the scientists prove that psilocybin can be produced de novo, which means that you can produce the molecule by simply growing the yeast with sugar and other nutrients,…

READ MORE
Science

Kratom… reduces neuropathic pain, study finds

Studies have shown that it may alleviate pain and aid in reducing alcohol and opioid dependence. The mechanisms for these actions are thought to be mediated through the mu, delta, and kappa opioid receptors… also has an affinity for several other receptor types that may be involved in its effects. Original Article (Psychedelic Review):Kratom compound…

READ MORE
Science

How microdosing magic mushrooms can change your life

Psilocybin-[containing mushrooms work] along a similar pathway to serotonin, which results in your brain producing a similar effect to serotonin. The main effect is to stimulate a serotonin receptor called “5-HT2A” which is found in the prefrontal cortex. Stimulating this receptor results in two key results. The first being triggering the production of “Brain Derived…

READ MORE