Psychology

How to get the dose right with psilocybin truffles

Below, [they will share their] calculations to match the doses of synthetic psilocybin used in 4 major and influential studies to the corresponding dose of magic truffles. Synthetic psilocybin is easy to measure and dose compared to raw mushrooms, and is therefore used exclusively in clinical trials. [Sclerotium are psilocybin fungus grown underground and share the same effects/ingredients as magic mushrooms.]

The exact psilocybin content of truffles is, as far as [they] can find, unknown, but going off of the calculation that 1 g of fresh truffles will contain between 0.75 and 1.75 mg of psilocybin, we have a reasonable window with which to find a comparable dosage of fresh truffles. Keep in mind that potency may vary by strain and that individual tolerance varies depending on both physiological and psychological factors (more on this another time). The information below is presented as a rough guide and calculated with fresh truffle weight. (If your truffles are dried, the equivalent dose will be significantly less. Fully dried truffles are approximately ⅓ the weight of fresh truffles. So for example, if the fresh truffle dose was 13g, you could calculate 13 / 3 =  to get a dried truffle dose of 4.33 g.) The best way to find the dosage right for you is through personal experience. Start low, document your sessions, and gradually work your way up.

10 mg psilocybin – Low dose
10 / 0.75 = 13.33
10 / 1.25 = 8
10 / 1.75 = 5.71

6 – 13 g fresh truffles
20 mg psilocybin – Moderate dose
20 / 0.75 = 26.66
20 / 1.25 = 16
20 / 1.75 = 11.43

11 – 27 g fresh truffles
25 mg psilocybin – High dose
25 / 0.75 = 33.33
25 / 1.25 = 20
25 / 1.75 = 14.29

14 – 33 g fresh truffles
30 mg psilocybin – High[er] dose
30 / 0.75 = 40
30 / 1.25 = 24

Original Article (Maps of the Mind):
How to get the dose right with psilocybin truffles
Artwork Fair Use: Drugs Lab

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