Science

[National Institutes of Health 2021 grant…] the neural correlates of the effects of psilocybin in OCD: randomized controlled study

Funding from the National Institute of Health [NIH], which tends to award larger grants than philanthropists, allows researchers to delve more into the details, Johnson says.

Grant Project Number 1K23MH122777-01A1: We hypothesize that psilocybin will result in increased (i.e. normalized) intra-DMN functional connectivity in OCD, and that this will correlate with any clinical change (Aim 1). Baseline DMN connectivity is anticipated to predict subsequent neural and clinical change (Aim 2). Finally, we will examine connectivity within the corticostriatal circuitry (Aim 3); while this circuitry has not previously been investigated in the context of psilocybin, it is robustly implicated in OCD. 

Original Article (NIH Report and Axios):
The neural correlates of the effects of psilocybin in OCD: randomized controlled study & The science of psychedelic therapy breaks on through
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