“Most psychedelic research has focused on the brain, but I became increasingly convinced that we were overlooking something crucial. This idea was reinforced by the growing field of somatic therapy and the way psychedelics seem to help reconnect people’s minds with their bodies,” said study author Valérie Bonnelle, an independent researcher who received a PhD…
U.S. Magistrate Judge Stanley A. Boone disagreed with Merrick Garland on all counts. “The court finds plaintiffs have sufficiently alleged a genuine threat of imminent prosecution … and this supports the conclusion that plaintiffs have demonstrated standing,” the judge states. “The court finds plaintiffs have sufficiently alleged a genuine threat of imminent prosecution … and…
…in a notice set to be published in the Federal Register on Wednesday [Jan. 3, 2024], DEA said it received comments from registered manufacturers requesting increases to previously proposed 2024 quotas for the Schedule I substances in order to “meet medical and scientific needs,” and it agreed to do so in the new final order.…
The researchers highlight that while their study is not the first to image the brain under the influence of psychedelics or the first to show the signatures of brain activity linked to psychedelics, it is the first to combine imaging techniques to study the brain during a highly immersive psychedelic experience. The fMRI scans found…
Two proposed initiatives. Under IP-59 [establishing regulated access by adults twenty-one years of age and older to natural medicine that show promise in improving well-being, life satisfaction, and overall health and the department shall have the authority to adopt rules that differentiate between natural medicines and that regulate each natural medicine differently… Local government impact.…
Be it Enacted by the People of the State of Colorado: SECTION 1: In Colorado Revised Statutes, 18-18-418 add subsections (7) and (8) as follows:18-18-418. (7) Notwithstanding any other provision of law, the following conduct is not a violation of State Law or the Laws of any locality within the State and no conduct permitted…
Significant growth was also observed at concentrations as low as 100 picomolar. These concentrations are well below measured levels in humans required to achieve psychedelic breakthrough. This initial data set is from… in vitro experiments designed to provide information on the dose and duration of infusion needed to achieve maximal cortical neurite outgrowth as well as…
Brain-derived neurotrophic factor (BDNF) regulates neuronal development and survival and triggers adaptive neuroplasticity… animal studies have reported that acute and chronic administration of various psychedelic compounds, including LSD, psilocybin, DMT, and other ayahuasca-derived alkaloids, can increase BDNF production and neurogenesis (the formation of new neurons). Importantly, threats to our well-being such as stress, ageing and…
DMT is a naturally occurring molecule which is found in hundreds of plants… secured approval to begin clinical trials with DMT. Research has suggested that people who’ve taken DMT, along with other psychedelics, can enjoy a long-lasting sense of connection with nature. A study that gave DMT to rats, meanwhile, found that it made them less anxious.…
These results support a recent model proposing that psychedelics reduce the ‘precision-weighting of priors’, thus altering the balance of top-down versus bottom-up information passing. The robust hypothesis-confirming nature of these findings imply the discovery of an important mechanistic principle underpinning psychedelic-induced altered states. The present analyses were applied to the first EEG data on the…
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