Significant growth was also observed at concentrations as low as 100 picomolar. These concentrations are well below measured levels in humans required to achieve psychedelic breakthrough. This initial data set is from… in vitro experiments designed to provide information on the dose and duration of infusion needed to achieve maximal cortical neurite outgrowth as well as…
Brain-derived neurotrophic factor (BDNF) regulates neuronal development and survival and triggers adaptive neuroplasticity… animal studies have reported that acute and chronic administration of various psychedelic compounds, including LSD, psilocybin, DMT, and other ayahuasca-derived alkaloids, can increase BDNF production and neurogenesis (the formation of new neurons). Importantly, threats to our well-being such as stress, ageing and…
DMT is a naturally occurring molecule which is found in hundreds of plants… secured approval to begin clinical trials with DMT. Research has suggested that people who’ve taken DMT, along with other psychedelics, can enjoy a long-lasting sense of connection with nature. A study that gave DMT to rats, meanwhile, found that it made them less anxious.…
These results support a recent model proposing that psychedelics reduce the ‘precision-weighting of priors’, thus altering the balance of top-down versus bottom-up information passing. The robust hypothesis-confirming nature of these findings imply the discovery of an important mechanistic principle underpinning psychedelic-induced altered states. The present analyses were applied to the first EEG data on the…
Less than 15 percent reported “judgmental or malicious” creatures. Almost 70 percent of people said they received some kind of message, task or insight from the entities they rubbed elbows with. Some were given predictions about the future or told the day they would die. Some were shown a way out of addiction. An online…
Scientists don’t really know why DMT users are far more likely to report encounters with mysterious entities than users of other… [psychedelics], but a new study recently published in the Journal of Psychopharmacology may shed some light on this phenomenon. Most subjects said the encounter was initiated by the entity, and most participants also said that they were…
More than 20 African countries have joined together in an international mission to plant a massive wall of trees running across the continent – and after a little over a decade of work, it has reaped great success. The initiative has since recruited at least nine additional countries to plant drought-resistant acacia trees across the…
Found in the ayahuasca tea made by the native people of the Amazon, and also produced naturally in our bodies… nearly 400 years after Descartes theorized about the gland, scientists are still trying to understand its role in humans. More than half of the subjects in Dr. Rick Strassman’s study reported interacting with intelligent beings…
Researchers from Imperial College London set out to look at the similarities between the DMT experience and reports of NDEs.. Their findings [were] published [in August 2018] in the journal Frontiers in Psychology, reveal a large overlap between those who have had NDEs and healthy volunteers administered DMT. Following each dosing session, the 13 healthy volunteers…
“Perhaps this foundation,” Davis said, could “eventually lead to studies that are able to answer the question about whether these experiences are hallucinations in the traditional sense of the word, (or) whether they are in fact ‘breakthrough’ experiences that lift a veil to another universe or into other parts of our own universe.” -Alan K.…
