Science

Shrooms and lsd linked to lower heart disease and diabetes risk

“The findings suggest that lifetime classic psychedelic use is associated with lower odds of having had heart disease or diabetes in the past year,” lead study author and Oxford sociologist Otto Simonsson, [said]. A team of scientists identified the unexpected trend after poring over ten years’ worth of data from the National Survey on Drug…

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Science

…psychedelics boost brain growth factor levels?

Brain-derived neurotrophic factor (BDNF) regulates neuronal development and survival and triggers adaptive neuroplasticity… animal studies have reported that acute and chronic administration of various psychedelic compounds, including LSD, psilocybin, DMT, and other ayahuasca-derived alkaloids, can increase BDNF production and neurogenesis (the formation of new neurons). Importantly, threats to our well-being such as stress, ageing and…

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Science

The psychedelic research hiatus and its relevance today

[In the 1950’s and 60’s] psychedelics were of little interest to pharmaceutical companies as the intervention seemed to treat illness, rather than alleviate symptoms. Consequently, the financial imperatives were lacking; fully recovered patients would not require continued medication… Sandoz was reluctant to share such proprietary and patented data (Bonson, 2018). When required by the FDA, the company…

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Biography/Memoir

NYC pharma startup wants to turn LSD into…

“…I want nothing to do with those kinds of folks who want to decriminalize psychedelics,” he says [a 32-year-old former Uber employee and co-founder]. …[he is part of] one of many companies trying to repurpose hallucinogenic molecules as the next blockbuster drug… has acquired the exclusive rights to eight clinical trials that are exploring the…

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Science

Magic mushrooms and LSD give sustained boost in mood after recreational use, study concludes

“Our results show that people who take psychedelics ‘in the wild’ report positive experiences very similar to those observed in controlled laboratory studies,” said lead author Matthias Forstmann. By surveying 1,242 UK and US festivalgoers over a four-year period, the researchers were able to characterise the psychological effects of the “afterglow” often documented in laboratory-based…

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Science

Acute subjective and behavioral effects of microdoses of LSD in healthy human volunteers

Single “microdoses” of LSD produced orderly dose-related subjective effects in healthy volunteers. Numerous anecdotal reports suggest that repeated use of very low doses of lysergic acid diethylamide (LSD), known as “microdosing,” improves mood and cognitive function. These effects are consistent both with the known actions of LSD on serotonin receptors, and with limited evidence that…

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