Science

Salvia divinorum [&] analgesic & anti-inflammatory action

October 13, 2021By

…the minutes-long hallucinogenic and dissociative effects of recreational S. divinorum in humans have been described in detail. Salvia divinorum… inhibited contractions of the mouse colon, stomach, and ileum in vitro; prolonged colonic propulsion; and slowed upper GI transit in vivo by activating KOR, CB1, and interestingly by activating cannabinoid type 2 receptors (CB2). In our laboratory, we…

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Psychology

…salvinorin…

October 13, 2021By

Published reports suggest potential benefits of Salvia divinorum in the treatment of TRD [treatment-resistant depression]. One doctor reported on 7 patients with TRD who described relief from depressive symptoms with triweekly oral consumption of salvia leaves. Several patients reported lasting benefits from their use of salvia, with significantly reduced scores on quantitative measures of depression. Patients…

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