Polymorphs B, A, and H… supported through Usona as an open access paper… peer-reviewed study… shows three most pharmaceutically relevant crystalline forms of psilocybin have been consistently created and observed since 1959. The ability of a unique crystalline arrangement to solidify in more than one form, called polymorphs, can be optimized using precise combinations of…
…microdosing psychedelics is technically not substance misuse because it does not involve taking drugs in excess or for an unintended purpose. The practice of microdosing psychedelics dates back to at least the early 16th century… to relieve fevers and rheumatism. The accepted definition of substance misuse is the use of prescription, illegal drugs, or over-the-counter drugs or…
Known as the Systematically Testing the Evidence on Marijuana… the project is a joint production of researchers with Oregon Health & Science University’s (OHSU) Center for Evidence-based Policy and the Veterans (VA) Portland Health Care System. …designed as an independent, methodologically rigorous resource primarily for health care workers. The site features living systematic reviews that…
Given the strikingly similar DMT entities reported by unconnected people from around the world, scientists are now attempting to understand more about the nature of these psychedelic characters… …a study… of the 2,561 DMT users surveyed by the Johns Hopkins team, 65 percent said their encounter filled them with “joy”, while 63 percent experienced a…
…repeatedly microdosed… zebrafish with LSD.… …using behavioural neuroscience tests to quantify locomotion, boldness and anxiety-like behaviour… we [also] found that zebrafish acutely dosed with the terpene limonene (found in citrus fruit peels and cannabis) and myrcene (found in cannabis and hops), showed a significant reduction in anxiety-like behaviour… [with terpene limonene & myrcene] no negative…
In a statement, Police National Drug Intelligence Bureau Manager Blair Macdonald said he was pleased with how this summer’s festival season had taken shape. …the Drug and Substance Checking Legislation Act, which was passed by Parliament in November 2021, has created a safer environment for people to get their drugs checked before they choose to…
In the paper, the authors highlight errors they discovered in the patent granted to COMPASS Pathways… COMPASS fell victim to that problem by not distinguishing between different crystalline forms. In other words, COMPASS fell victim to the problem it claimed to solve. The Petition claims that COMPASS Pathways never reported the crystal structure for its…
Instead of holding on tightly to trade secrets… MAPS paper… read as a step-by-step production recipe, the study maps out how MDMA with a purity of 99.4% can be made from non-controlled substances… describes a process of making MDMA according to “current Good Manufacturing Processes” (cGMP), with the end product being 30.000 (167mg) individual doses……
Adding psychedelics to mainstream drugs may seem a bit “out there,” but in fact it’s on trend… Synthetic versions of psychedelic substances are easier to manufacture uniformly according to industry standards, but they may not work as well as natural versions. “We believe there’s a big difference between biological and synthetic molecules, especially in how…
The consumption of alcoholic beverages is responsible for 5.3 percent of deaths worldwide every year… in both groups of mice that received psilocybin, mGluR2 expression was restored following the treatment. This change was evident in the mice’s behavior, too: The psilocybin group relapsed roughly 45 percent less compared to the control mice. As hypothesized, mGluR2 expression was reduced in the brains…
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