…patent challenge targets crystallography errors
In the paper, the authors highlight errors they discovered in the patent granted to COMPASS Pathways… COMPASS fell victim to that problem by not distinguishing between different crystalline forms. In other words, COMPASS fell victim to the problem it claimed to solve.
The Petition claims that COMPASS Pathways never reported the crystal structure for its Form A. Accordingly, they never confirmed (by solving the crystal structure) that they had isolated a single crystalline form of psilocybin. Rather, they relied on PXRD data to define only Form A and that technique did not alert the scientists to the presence of multiple crystalline forms. This oversight ultimately opened the door for the recent patent challenge after studies by Sherwood et al. revealed errors in COMPASS’ use of PXRD data to distinguish its Form A as a novel crystalline form.
Original Article (Psychedelic Science Review):
COMPASS patent challenge targets crystallography errors
Artwork Fair Use: Sheila Sund