[Psilocybe] mushroom extract [appears] more effective than pure psilocybin in reducing OCD symptoms in mice
Anecdotal and experimental evidence exists showing that the entourage effect is also at work with the compounds found in magic mushrooms…
In this study, the research team compared the effects of an extract from Psilocybe argentipes to pure psilocybin using MBB (marble burying behavior) and 5-week old male mice. The results of the study showed that the same dose of the mushroom extract and pure psilocybin were effective in reducing marble-burying behavior. But even more interesting was the finding that the psilocybin mushroom extract was more effective at the same dose in reducing the behavior than pure psilocybin alone. A dose of 0.1 to 1.0 g/kg was significant in reducing the number of buried marbles without affecting the overall locomotor activity of the mice.
Original Article (Psychedelic Review):
Psilocybin mushroom extract more effective than pure psilocybin in reducing OCD symptoms in mice
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