Science

[Beer… coffee… fentanyl…]

….beer twice as expensive… That’s because the cost of a key ingredient, malted barley, could soar as…barley becomes harder to grow. The price of a six-pack in the United States might rise by as much as $8 on average, the study found… [coffee] six-in-ten of the known species of coffee are now under threat of…

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Anti-inflammatory effects of four psilocybin-containing magic mushroom [psilocybe & panaeolus] water extracts 

Mushrooms were grown and extracted with boiling hot water. Effects of the four water extracts on 15-LOX activity were determined… natural [fungi] with medicinal properties have been used to treat all sorts of inflammatory conditions and studies have shown that natural products have advantageous structural diversity over synthetic compounds, which thus make them a potential…

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Comparing… mushrooms and truffles…

…psilocybin truffles have “a lot of psilocybin but little psilocin.” This hypothesis is corroborated in the literature. …, Pellegrini et al. reported: “…no trace of psilocin could be found at least at the limit of the detection of the assay” (0.3 µg per 100 mg truffles). In stark contrast, a 2019 study… found that a…

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…to define…

So what has science been able to offer since Shulgin? There have been at least two contributions to the field: The first is the structural determination of a psychedelic-bound 5-HT2A receptor at near-atomic resolution. These reconstructions have enabled detailed computer simulations to identify thousands of candidate compounds which can be tested to evaluate their kinetic…

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Myriad new drugs…

…by definition, the compounds are new and poorly understood… most people who use drugs wouldn’t want to use most NPS anyway, if better-known and better-studied equivalents were legally and widely accessible. An effort out of the University of Copenhagen called HighResNPS collects mass spectrometry data on novel psychoactive substances (NPS) from around the world. Its list, which…

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…magic mushroom… smell loss?

Later that night, he reveled in the enchiladas they had for dinner. “I could taste the individual ingredients,” he said. “I mean, it’s not anything I’d wish on anybody to lose their sense of smell, but to lose it and have it come back that abruptly was really — it was a special experience.” Neuroscientist…

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Fentanyl found… bring fentanyl test strips…

Lane County Public Health’s prevention supervisor, Elisabeth Maxwell has been watching the crisis closely. She said it’s been going on for years… Naloxone, also known as Narcan, can be used to reverse an opioid overdose. Investigators with the Eugene Police Department are on high alert for mass overdose events. They report that fentanyl is found…

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Magic mushrooms… DNA is now available online

On the academic front, over 84 fully sequenced genomes from different psilocybe mushrooms… …were published online with open access… now, everyone can access… psilocybin genomic library. Original Article (Bengazi):Magic mushrooms have over 80 different species – and their DNA is now available online & DNA From 80 psilocybe mushrooms published onlineArtwork Fair Use: Prokofiev

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…alter your understanding…

…the social ramifications engendered by taking psychedelics have alarmed state security apparatuses, historically speaking… only 26 percent of participants attributed consciousness to plants prior to their psychedelic experience; afterwards, that number jumped to 61 percent. The jump for fungi was comparable. These impacts persisted with survey respondents reporting an average of eight years after the…

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