Science

Love drugs might be the future of relationships

…a new wave of research is exploring the therapeutic uses of other substances such as magic mushrooms, MDMA and LSD, not just as party drugs but as real-life neurotechnologies that can act as a chemical nudge on the brain systems involved in love and attachment. …let’s not forget, love itself is also not to be taken lightly. Instead of…

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Virtual library of LSD-like drugs could reveal new antidepressants

…researchers have built a virtual library of 75 million compounds related to these drugs. This approach yielded two molecules that showed antidepressant properties in mice, but without the hallucinogenic activity of psychedelic drugs. Original Article (Nature):Virtual library of LSD-like drugs could reveal new antidepressantsArtwork Fair Use: Jimmy-neutron

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Large national survey suggests that the use of psychedelics is not associated with lifetime cancer development

When controlling for confounding variables, the results revealed that lifetime psychedelic use was not associated with lifetime cancer diagnosis nor hematologic cancer diagnosis. This was true for each of the three classifications of psychedelics: tryptamine (5-MeO-DIPT, AMT, DMT), lysergamide (LSD), and phenethylamine (2C-B, mescaline, MDMA, peyote, and San Pedro). “Beginning in the late 1960s, concerns were raised by laboratory experiments that…

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Scientists to examine how mushrooms become magic

…people have… found that compounds such as psilocybin can have psychotherapeutic benefits. However, that has not addressed their evolution in nature… …scientists from the University of Plymouth are conducting a first-of-its-kind study using advanced genetic methods and behavioral experiments to address previously untested hypotheses into the origin of psychedelic compounds in fungi. Original Article (Phsy.org):Scientists to…

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What does kratom do?

While there is always room for more research to be conducted, as of now, studies have shown that kratom has many benefits… kratom leaf has been chewed for at least 150 years in Southeast Asia… Kratom has been shown in studies to have antidepressant and appetite-suppressant properties. In one animal research, researchers discovered that kratom…

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How does psilocybin rewire the brain?

60 people participated in two psilocybin trials and had their fMRI brain scans analysed by scientists… scans were taken before and after treatment… The results showed that the psilocybin treatment reduced connections within brain areas that are tightly connected in depression. According to this research, scientists found that psilocybin rewires the brain for up to…

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How MDMA resensitizes the brain

…in mice, MDMA can reopen the critical period for social learning after it should have closed permanently. In 2019, neuroscientist Gül Dölen’s laboratory at Johns Hopkins University in Baltimore, Maryland, found that the psychedelic drug MDMA resensitizes the brains of adult mice so they can learn from their social environment in a way that’s normally…

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Decreases in state and trait anxiety post-psilocybin: a naturalistic, observational study…

Anxiety disorders are the most common type of psychiatric disorders among Western countries. Evidence-based treatment modalities including pharmacological and cognitive-behavioral therapy result in deficient treatment responses… the raw data supporting the conclusions of this article will be made available by the authors, without undue reservation… the authors declare that the research was conducted in the…

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…social… with psychedelics…

…we are planning a study right now using a citizen-scientist approach, says Sonja Lyubomirsky, a psychologist at UC Riverside. We’re going to ask people to get together with a friend and have a deep conversation. We’re going to have a placebo, which may be either a lower dose of the drug, or it could be…

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Psychedelic drugs… brain’s dynamic landscape

…LSD and psilocybin activate serotonin receptors on brain cells in a way that reduces the energy needed for the brain to switch between different activity states, according to a study led by Weill Cornell Medicine researchers… “Serotonin 2a receptors have a spatial distribution in the brain that appears to be optimized for lowering these state…

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