Science

How long is… [LSD] detectable in the body? [A 12-step summary]

LSD is unstable, and the liver breaks it down rapidly. The time that LSD is detectable in the tissues is restrictive, so doctors need to analyze the samples quickly. *this article is a generalization, and not intended to replace the original source article. please view the original source article for full and detailed description, including…

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Effects of ‘secondhand drinking’ hurt 53 million Americans: study

The most common type of harm reported was threats or harassment. Forget secondhand smoke. Now you have to worry about the secondhand drinking. One fifth of adults — or an estimated 53 million people in the United States — suffer from other people’s boozing annually, making this “a significant public health issue,” according to a new…

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Acute subjective and behavioral effects of microdoses of LSD in healthy human volunteers

Single “microdoses” of LSD produced orderly dose-related subjective effects in healthy volunteers. Numerous anecdotal reports suggest that repeated use of very low doses of lysergic acid diethylamide (LSD), known as “microdosing,” improves mood and cognitive function. These effects are consistent both with the known actions of LSD on serotonin receptors, and with limited evidence that…

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CBD and the psychedelic receptor

CBD and… [psilocybin] act at 5-HT2A, the psychedelic receptor, in different ways, resulting in markedly different effects. Whereas CBD has little binding affinity for the classical cannabinoid receptors, CB1 and CB2, several serotonin receptor subtypes are key docking sites for CBD, [including the 5-HT2A]. Original Article (Project CBD):CBD and the psychedelic receptorArtwork Fair Use: DrLee

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Hemp fibres ‘better than graphene’

Electric cars and power tools could harness this hemp technology, the US researchers say. The waste fibres from hemp crops can be transformed into high-performance energy storage devices, scientists say. They “cooked” cannabis bark into carbon nanosheets and built supercapacitors “on a par with or better than graphene” – the industry gold standard. Original Article…

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Chronic marijuana use in male teens not linked to later issues [according to American Psychological Association]

Bechtold was expecting to find a link between teen marijuana use and a variety of later symptoms. But the study found that both physical ailments (such as cancer, asthma and respiratory problems) and mental ailments (such as lifetime depression and anxiety), were equally likely for non-marijuana users and frequent smokers … the results were published…

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30 years after Prozac arrived, we still buy the [theory] that chemical imbalances cause depression

This doesn’t mean that antidepressants that affect levels of serotonin definitively don’t work—it simply means that we don’t know if they’re affecting the root cause of depression. A drug’s effect on serotonin could be a relatively inconsequential side effect, rather than the crucial treatment. A conglomeration of factors, beginning in the 1960s but having the…

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Baeocystin: an ignored magic mushroom compound

Baeocystin was first isolated by Leung and Paul in 1968 from the mushroom Psilocybe baeocystis (hence the name). Other researchers later isolated it from Psilocybe semilanceata, Panaeolus renenosus, Panaeolus subbalteatus, and Copelandia chlorocystis. Jochen Gartz refers to a report that “10 mg of baeocystin were found to be about as psychoactive as a similar amount of psilocybin.” Although the presence…

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The ensemble/entourage effect in magic mushrooms

In a 1989 paper, the German scientist, researcher, and author Jochen Gartz used keen insight to analyze the data from 24 cases of accidental ingestion of the magic mushroom Inocybe aeruginascens. He also examined data on the effects of ingesting species with high psilocybin and psilocin content. From his analysis, he proposed an entourage effect in magic…

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