Effects of external stimulation on psychedelic state neurodynamics
Stronger external stimulation increases baseline entropy and reduces the drug effect.
Results show that while brain entropy increases with LSD under all of the experimental conditions, it exhibits the largest changes when subjects have their eyes closed. Furthermore, brain entropy changes are consistently associated with subjective ratings of the psychedelic experience, but this relationship is disrupted when participants are viewing a video potentially due to a “competition” between external stimuli and endogenous LSD-induced imagery. We calculated Lempel–Ziv complexity (LZ; see below) on these locations and finally mapped them back onto the standard template for statistical analysis and visualization… we computed LZ in sources reconstructed in a uniform 10 mm three-dimensional (3D) grid.
Original Article (Westword):
Effects of external stimulation on psychedelic state neurodynamics
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