Science

Magic mushroom… ameliorates some cognitive deficits in autistic…

Microdoses of psilocybin… have been found to normalize certain elements of cognitive performance in young rats with autism. And while it’s far too early to say if the drug produces the same benefits in humans with autism spectrum disorder (ASD), the fact that larger doses of psilocybin were less effective in rats does at least lend some credibility to the… topic of psychedelic microdosing.

For example, in neurotypical children, serotonin levels peak between the ages of two and five, when synthesis of this key transmitter chemical is roughly double that seen in the adult brain. However, serotonin production tends to be considerably lower in autistic children, and increases gradually over the years rather than racing towards a peak in early childhood. Low serotonin concentrations also correlate with more severe Fragile x syndrome, (FXS), which is the leading monogenic cause of Autism spectrum disorder (ASD) in humans… symptoms, including increased aggressive and stereotypic behaviors. However, because psilocybin and other psychedelics exert their effects primarily by activating the brain’s serotonin receptors, the study authors hypothesized that the drug may help to alleviate some of these deficits.

Original Articles (ILF Science):
Magic mushroom compound ameliorates some cognitive deficits in autistic rats
Artwork Fair Use: Joe-Schraube

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