Your set and setting greatly influence how and when and where this happens, not always in a predictable way. Under-dosing (or low dosing), for example, can help you navigate the strange in-between of being neither here nor there, not fully able to communicate with either the sober or altered worlds. Moderate dosing can teach you…
We can think of the ego as three components. Self-Image. The view an individual holds of themselves. Self-Esteem. How much value an individual places on themselves. Self-Identity. The many beliefs, opinions, ideologies, and affiliations that an individual holds… Researchers from Imperial College London have found that the mystical experience drives the efficacy of psychedelic therapy. Patients…
Psychedelics may reopen “critical periods” in neurodevelopment… A hypothesis puts forward evidence for a model of the co-evolution and advantages to the consumption of psychedelics by humans in pre-history. Four factors may have contributed to the inclusion of psychedelics in their diet: 1) management of psychological distress, 2) enhanced social interactions, 3) facilitation of collective rituals, and 4)…
…some Native Americans would travel up to 322 kilometers (200 miles) on foot to attain the peyote… even the process of acquiring the peyote, called “the hunt,” is a part of the ritual. Since its scientific discovery around the turn of the 20th century, peyote use has expanded. Now, many people use the plant or its…
…the minutes-long hallucinogenic and dissociative effects of recreational S. divinorum in humans have been described in detail. Salvia divinorum… inhibited contractions of the mouse colon, stomach, and ileum in vitro; prolonged colonic propulsion; and slowed upper GI transit in vivo by activating KOR, CB1, and interestingly by activating cannabinoid type 2 receptors (CB2). In our laboratory, we…
Published reports suggest potential benefits of Salvia divinorum in the treatment of TRD [treatment-resistant depression]. One doctor reported on 7 patients with TRD who described relief from depressive symptoms with triweekly oral consumption of salvia leaves. Several patients reported lasting benefits from their use of salvia, with significantly reduced scores on quantitative measures of depression. Patients…
“The findings suggest that lifetime classic psychedelic use is associated with lower odds of having had heart disease or diabetes in the past year,” lead study author and Oxford sociologist Otto Simonsson, [said]. A team of scientists identified the unexpected trend after poring over ten years’ worth of data from the National Survey on Drug…
For a regulating body like the FDA, researchers aiming to put a psychedelic drug and treatment through the clinical research pipeline only need to prove two things: that the drug (and its associated protocols) are safe, and that they work successfully at treating the indication they’re after. While multiple psychedelic substances are currently undergoing dozens…
The future of psychedelic therapy is also uncertain. While it seems likely that at least some psychedelic drugs will be approved for certain medical conditions in the years to come, it’s also possible that recreational use could be widely decriminalized or legalized. The status quo could also stay in place. The companies and people hoping…
A megadrought across the West has created urgency, though, as illegal growers steal water, depriving legal users including farmers and homeowners of the increasingly precious resource. “Jackson County strongly requests your assistance to address this emergency,” the commissioners said in a letter to Gov. Kate Brown, Senate President Peter Courtney and House Speaker Tina Kotek. Josephine…
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