Psychology

Microdoses of LSD show antidepressant effects in placebo-controlled study

…researchers at the University of Chicago have discovered that low doses of lysergic acid diethylamide (LSD), a psychedelic drug, may have potential antidepressant effects in individuals showing mild to moderate depressive symptoms… the findings have been published in the journal Neuropsychopharmacology. “There has been a great deal of public interest in ‘microdosing,’ or the idea…

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Science

…thousands of possible psychedelics

“AlphaFold is an absolute revolution. If we have a good structure, we should be able to use it for drug design,” says Jens Carlsson, a computational chemist at the University of Uppsala in Sweden. Efforts to apply AlphaFold to finding new drugs have been met with considerable skepticism, says Brian Shoichet, a pharmaceutical chemist at…

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Science

Chronic lower back pain: Can a psychedelic… come to your rescue?

“It’s a massive problem,” said Patrick Finan, the Harold Carron Professor of Anesthesiology in the School of Medicine and the co-principal investigator for the trial. “Chronic lower back pain is growing in prevalence, particularly as people age and medicine improves to keep people active longer.” Finan said there is encouraging research now that psilocybin may…

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Science

…kratom extracts

History has shown that developing enriched natural product elixirs or purified active agents, as with cocaine from the coca shrub and morphine from the opium poppy, can be both a blessing and a curse. Concentrated kratom extracts are analogous to these historical examples. Though the extracts may provide benefits to some, they may also result…

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Biography/Memoir

California… ‘magic mushrooms’

An initiative that sought to ask voters to decriminalize so-called magic mushrooms and products containing psilocybin failed to qualify for the 2024 ballot when it missed last week’s deadline to submit signatures. That followed Gov. Gavin Newsom’s veto last year [2023] of a bill that would have decriminalized a short list of natural psychedelics, including “magic mushrooms.”…

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Science

Cannabis holds potential to prevent and reduce severity of COVID-19, while treating long-term symptoms, study finds

Researchers at Dalhousie University in Canada carried out a comprehensive review of the scientific literature, publishing their findings about marijuana as a preventive therapeutic in the Journal of Clinical Medicine… The study found that “cannabinoids have been shown to prevent viral entry, mitigate oxidative stress, and alleviate the associated cytokine storm” of early COVID-19 infections.…

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