HPPD is incredibly rare… In the 1960’s and the 1970’s, an estimate surfaced to show 1 in 20 people with hallucinogenic experiences had intermittent cases of HPPD. Fast forward to the 1990’s, and it was believed to be 1 in 50,000 regular users have chronic HPPD… Countless anecdotes from HPPD… sufferers vouch for the effects…
There have been several FDA-approved medications with 5HT2B receptor activation withdrawn from the US market due to the risk of VHD with heart valve thickening and murmurs: Fen-Phen (fenfluramine/phentermine) and Redux (dexfenfluramine) in 1997 and Permax (pergolide) in 2007. Roughly 25% of patients taking these medications daily developed new onset VHD according to incidence statistics…
Samples testing positive for fentanyl also tested positive for meth rose almost 14-fold… and by more than sixfold for cocaine and heroin. Similarly, the percentage [of] tests coming back positive for the highly potent — and sometimes fatal — opioid fentanyl have more than quadrupled since 2013, the study found. Original Article (UPI):Meth use up…
Based on what is known about the cannabinoids in cannabis plants… …it is plausible that there is synergy going on between the multiple active and inactive compounds in these mushrooms. Magic mushrooms contain more than just psilocybin … seemingly minor differences in the chemical structures can have dramatic effects on the cellular and clinical pharmacology of…
Magic mushrooms are officially your safest [psychoactive], according to… scientists. Only 0.2 percent of users, male and female, who had [consumed psilocybe mushrooms] reported having to undergo emergency treatment. This is compared to a global average of 4.8 percent of meth users, 3.2 percent of synthetic weed smokers and 1.3 percent of [alcohol drinkers]. Original Article…
Scientists highlight a critical factor in the study that the consumption of pure, isolated psilocybin may not have the same effects has mushroomed in their natural form. Cannabis has similar evidence when it comes to consuming the whole plant, which some can create an “entourage effect” that is more potent than consuming any individual cannabinoid in isolation.…
The drugs that are the most dangerous, including methamphetamine and heroin, are water-soluble drugs that leave the human body relatively quickly. Simply put, unless somebody literally just did one of these drugs within hours before a test, they stand a very good job of passing the test. Inaccurate cannabis drug testing undoubtedly keeps a significant…
A July 21, 2019 article in the American Chemical Society’s Chemical & Engineering News by Britt E. Erickson… discussed the importance of the entourage/[ensemble] effect in cannabis health. Like magic mushroom fruiting bodies, cannabis plant material includes multiple active ingredients (cannabinoids, terpenoids, and other “minor components”), which modulate its biological and clinical properties. Original Article (Psilocybin Technology):Chemical &…
Famous author Michael Pollan succinctly summarized this apparent lack of incentive for developing psilocybin “technology”: “there’s no IP here. There’s no intellectual property.” Both Cannabis and Psilocybin Mushrooms are naturally occurring organisms. They live and grow in nature. Each plant or mushroom produces its own cocktail of chemical compounds — cannabinoids, terpenes, psilocybin [mushroom containing bioactive compounds], etc… Why…
Data suggests that psilocybin is far less potent than a drug like LSD and that it carries a very low risk of overdose toxicity (estimated to be 1,000 times an effective dose), but it can still produce negative effects. It is unclear how psilocybin might produce therapeutic benefits that span months despite only being acutely effective for a few hours.…
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