Science

Psilocybin enhances insightfulness in meditation: a perspective on the global topology of brain imaging during meditation

…in which a novel topological data analysis (TDA) method is applied to the neurophysiological study of the synergistic effects of meditation and psychedelics. …intriguing evidence of similarities in the phenomenology and neurophysiology of meditation and psychedelics has been found… recent reviews suggest that meditation and psychedelics exhibit similarities and complementary differences, which may indicate potential…

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Medicine/Healing

Do dying people have a ‘right to try’ magic mushrooms? 9th Circuit weighs case

That question is now before one of the nation’s highest courts… …pitting the DEA’s law enforcement authority against state powers to regulate medicine… Washington, Washington D.C., Delaware, Illinois, Michigan, Minnesota, Nevada, Oregon and Pennsylvania… have weighed in directly… the state coalition filed a brief that accused the DEA of reaching far beyond its law enforcement…

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Psychology

…psilocybin shop reopens after two police raids in one week

…it appears as though the owners of psilocybin shops have no plans to shut down for good. “This is like some kind of terrible drug war anachronism from some other era that shouldn’t even be on the books and we’re hopefully going to change that,” FunGuyz lawyer Paul Lewin. According to the former Ontario Provincial…

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Science

Magic mushrooms can treat medication-resistant depression. Are they safe? A systemic review and meta-analysis

What are the notable acute adverse effects for therapeutic doses of psilocybin in the treatment of depression and anxiety? [Date Sources:] MEDLINE via PubMed, Web of Science, and ClinicalTrials.gov were searched for publications available between 1966 and November 30, 2023. In this meta-analysis of 6 randomized, double-blind clinical trials with 528 patients, headaches, nausea, anxiety,…

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Spirituality

…‘psychedelic church’ to provide support services for… 4/20 event

The Church of Ambrosia, a self-described “psychedelic church,” announced it will be providing support services on Hippie Hill Saturday, “cancellation or not.” …the church said it would be partnering with local Haight Ashbury merchants and nonprofit groups to provide a basic “safety net” of services like water, medical aid, portable toilets, and trash pickup. Original…

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Science

Decoding psilocybin: “magical” enzymatic pathways…

Psilocybin is formed by fungi in complex biochemical processes from the amino acid L-tryptophan. The enzyme PsiM, a methyltransferase, plays an important role in this process. It catalyzes two methylation reactions in succession, the last two steps in the production of psilocybin. …a team from the Medical University of Innsbruck led by crystallographer Bernhard Rupp and the…

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