The FDA declined to approve the new treatment submitted by Lykos Therapeutics, an organization that develops innovations to “transform mental healthcare,” deciding that there still isn’t enough evidence of benefit to outweigh the risks. The decision will have far-reaching ripple effects. Some psychedelic advocates will have to put celebrations they’ve been planning for decades on pause;…
A 77-year-old retired Marine Corps general has emerged as an unlikely advocate for treating veterans suffering from post-traumatic stress disorder with the psychedelic drug ecstasy… Jack Bergman flew helicopters in Vietnam, earned three stars, and is now in his fourth term representing a northern Michigan district in the House. A Republican, he sees promise in…
The results showed that the two pharmacological interventions created significantly different hierarchical reconfigurations of whole-brain dynamics… the main hypothesis is that psychedelics can bring about a relaxation of the precision of high-level priors or ‘beliefs’ (REBUS), allowing (anarchic) bottom–up information flow, consistent with ‘anarchic’ (that is, hierarchy-free) system dynamics. This theory is consistent with our…
Question: I heard magic mushrooms have strains, just like cannabis. Is that true? Answer: There are a lot of parallels between the two… and although they all have psilocybin, they’re not all the same. These mushrooms have other tryptamines and alkaloids… specific mushrooms have shown potential in treating specific mental and physical ailments, according to…
“Due to the age of the plants, Watermasters estimate that roughly 1.5 million gallons of water was saved by stopping water use at this time,” JCSO (Jackson County Sheriff’s Office), explained. “While regulatory agencies investigate permitted cannabis operations, IMET is focusing on the black-market marijuana trade in the Rogue Valley,” the agency said. “IMET is…
It has been proposed that psychedelics promote wellbeing through spiritual-type transformations, involving changes in metaphysical beliefs… the results indicate that Idealism specifically, not non-physicalist beliefs generally, mediate a link between the use of psychedelics and wellbeing… metaphysical beliefs are typically abstract and non-falsifiable… In terms of predictive coding neuroscience, such as the free energy principle,…
Researchers at the University of California, Davis have developed a rapid, noninvasive tool to track the neurons and biomolecules activated in the brain by psychedelic drugs. The protein-based tool, which is called Ca2+-activated Split-TurboID, or CaST… This research provides scientists with a new technique that could be used to track step by step the molecular…
…so if we’re going to consider the retail sale of psychedelics… public conversation about how a retail psychedelic market might actually work has been all but nonexistent. So far, most debate over how to expand legal access to psychedelics has focused on segmented approaches like therapy, religious exemptions, or supervised retreat centers. The reports from Transform and RAND…
The study was conducted using 66 male Long-Evans rats, which were chosen based on their suitability for modeling human alcohol consumption behaviors. They were housed individually under a controlled light/dark cycle and had unlimited access to food and water. The study followed strict ethical guidelines for the care and use of laboratory animals. Initially, the…
Those who take psychedelics say they maintain their sobriety because the plant-based psychedelic is non-addictive and is being used medicinally or for spiritual enlightenment — not to numb out. “Members are being punished and expelled from their recovery groups and fellowships due to ignorance, judgment and misinformation in direct violation of our traditions,” Vanessa Crites,…
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