Science

Anti-inflammatory effects of four psilocybin-containing magic mushroom [psilocybe & panaeolus] water extracts 

Mushrooms were grown and extracted with boiling hot water. Effects of the four water extracts on 15-LOX activity were determined… natural [fungi] with medicinal properties have been used to treat all sorts of inflammatory conditions and studies have shown that natural products have advantageous structural diversity over synthetic compounds, which thus make them a potential…

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Comparing… mushrooms and truffles…

…psilocybin truffles have “a lot of psilocybin but little psilocin.” This hypothesis is corroborated in the literature. …, Pellegrini et al. reported: “…no trace of psilocin could be found at least at the limit of the detection of the assay” (0.3 µg per 100 mg truffles). In stark contrast, a 2019 study… found that a…

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…to define…

So what has science been able to offer since Shulgin? There have been at least two contributions to the field: The first is the structural determination of a psychedelic-bound 5-HT2A receptor at near-atomic resolution. These reconstructions have enabled detailed computer simulations to identify thousands of candidate compounds which can be tested to evaluate their kinetic…

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Myriad new drugs…

…by definition, the compounds are new and poorly understood… most people who use drugs wouldn’t want to use most NPS anyway, if better-known and better-studied equivalents were legally and widely accessible. An effort out of the University of Copenhagen called HighResNPS collects mass spectrometry data on novel psychoactive substances (NPS) from around the world. Its list, which…

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…magic mushroom… smell loss?

Later that night, he reveled in the enchiladas they had for dinner. “I could taste the individual ingredients,” he said. “I mean, it’s not anything I’d wish on anybody to lose their sense of smell, but to lose it and have it come back that abruptly was really — it was a special experience.” Neuroscientist…

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Fentanyl found… bring fentanyl test strips…

Lane County Public Health’s prevention supervisor, Elisabeth Maxwell has been watching the crisis closely. She said it’s been going on for years… Naloxone, also known as Narcan, can be used to reverse an opioid overdose. Investigators with the Eugene Police Department are on high alert for mass overdose events. They report that fentanyl is found…

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Magic mushrooms… DNA is now available online

On the academic front, over 84 fully sequenced genomes from different psilocybe mushrooms… …were published online with open access… now, everyone can access… psilocybin genomic library. Original Article (Bengazi):Magic mushrooms have over 80 different species – and their DNA is now available online & DNA From 80 psilocybe mushrooms published onlineArtwork Fair Use: Prokofiev

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Magic mushrooms… only one fast-growing species… Oregon

No matter the species, growing “magic” mushrooms is relatively cheap. …”magic” mushroom species… grow in the Pacific Northwest. Not every mushroom expert agrees with Oregon’s decision to hone in on one “magic” mushroom species. [Out of about 200 mushrooms, there’s (approximately) four of them that cause wood-lovers paralysis]. Original Article (Business Insider):‘Magic’ mushrooms will be…

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[Fungal biology]… thousands of years…

…there are more than 300 species of psilocybin-containing mushrooms… A paper published in the journal Fungal Biology summarizes centuries of psilocybin use among shamans and guides who treated people for a host of ailments, from anxiety and rheumatism to toothaches and stomach pain… A study published in Evolution Letters sets out the evidence for this…

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