Science

Baeocystin: an ignored magic mushroom compound

Baeocystin was first isolated by Leung and Paul in 1968 from the mushroom Psilocybe baeocystis (hence the name). Other researchers later isolated it from Psilocybe semilanceata, Panaeolus renenosus, Panaeolus subbalteatus, and Copelandia chlorocystis. Jochen Gartz refers to a report that “10 mg of baeocystin were found to be about as psychoactive as a similar amount of psilocybin.” Although the presence…

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The ensemble/entourage effect in magic mushrooms

In a 1989 paper, the German scientist, researcher, and author Jochen Gartz used keen insight to analyze the data from 24 cases of accidental ingestion of the magic mushroom Inocybe aeruginascens. He also examined data on the effects of ingesting species with high psilocybin and psilocin content. From his analysis, he proposed an entourage effect in magic…

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Phenylethylamine: an… active compound in magic mushrooms

Consider these facts about phenethylamine … [Love-related chemical. Carbon = black hydrogen = white nitrogen = blue] … [The brain’s best known love chemical is phenylethylamine, or PEA. It is a naturally occurring amphetamine. “Love is a drug,” says Helen Fisher, an anthropologist at Rutgers University and author of Anatomy of Love.] It acts as…

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Ketamine: can it really be an antidepressant?

Experts warn that it isn’t necessarily a “miracle cure” – it can come with side-effects and nothing is known about the risks of using it long term. [Afterall], the [patient outcome] results were decidedly mixed and some scientists have pointed out that the FDA relaxed its usual rules for accepting drugs, in order to let…

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FDA approves… [dissociative anesthetic] nasal spray for depression

[The FDA approved spray] is a chemical mirror image of anesthetic ketamine. The treatment comes with a boxed warning — FDA’s harshest — flagging the risk for sedation and difficulty with attention, judgment and thinking, abuse and misuse, and suicidal thoughts after administration of the drug. Original Article (CNBC):FDA approves… [dissociative anesthetic] nasal spray for depressionArtwork Fair Use: Yair…

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‘Hangxiety’: why alcohol gives you a hangover and anxiety

Alcohol, he says, targets the Gaba (gamma-aminobutyric acid) receptor, which sends chemical messages through the brain and central nervous system to inhibit the activity of nerve cells. Put simply, it calms the brain, reducing excitement by making fewer neurons fire. “Alcohol stimulates Gaba, which is why you get relaxed and cheerful when you drink,” explains…

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Experts are concerned that kratom will become the next marijuana

*[will governments continue to] deny the entourage effect of whole plant botanicals, ban home-grown plants, force consumers to pay for synthetic pills, or go into the black market if they are low-income and/or have no health insurance coverage, increase profits for the treatment industrial complex A ban wouldn’t just impact the estimated 3 to 5 million Americans who use…

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