The ensemble/entourage effect in magic mushrooms
In a 1989 paper, the German scientist, researcher, and author Jochen Gartz used keen insight to analyze the data from 24 cases of accidental ingestion of the magic mushroom Inocybe aeruginascens. He also examined data on the effects of ingesting species with high psilocybin and psilocin content. From his analysis, he proposed an entourage effect in magic mushroom compounds.
Dr. Gartz noticed that the people who ingested I. aeruginascens reported only euphoric experiences. He contrasted these experiences to accounts from people who used magic mushrooms with high psilocybin and psilocin content for hallucinogenic purposes. He described these experiences as an “often slight and in some cases deep dysphoric mood” accompanied by psychosis, panic, and anxiety. Additional evidence of the magic mushroom entourage effect was published by Zhuk and colleagues in 2015 … The authors concluded that their data “confirmed the strong synergistic interaction of psychotropic components of used fungal mushrooms.” … [by way of] synergistic effects.