How long is… [LSD] detectable in the body? [A 12-step summary]
LSD is unstable, and the liver breaks it down rapidly. The time that LSD is detectable in the tissues is restrictive, so doctors need to analyze the samples quickly.
*this article is a generalization, and not intended to replace the original source article. please view the original source article for full and detailed description, including links to various scientific sources.
1. Detectability of LSD through “testing” is restrictive in the nature of the results it provides.
2. Generally speaking, the amounts of LSD remain low in the tissues.
3. Essentially, quick detection is needed from time of ingestion.
4. Even then, standard (typical) urine tests are not useful.
5. Researchers, therefore, will sometimes test for byproducts of LSD, though researchers are uncertain how these findings can help detect LSD use, however.
6. Therefore, expensive tests not readily available to doctors (they are highly sensitive and specialized) such as liquid-liquid extraction and ultra-high-performance liquid chromatography-tandem mass spectroscopy (UHPLC-MS/MS) are sometimes used. They can be used to detect LSD in the body.
7. In urine, in 24 hours, a person excretes only about 1% of LSD unchanged.
8. Within 24 hours of taking LSD, some tests can detect it in blood samples. However, in drawn blood, researchers could only detect the drug in 9 out of 24 samples after 16 hours.
9. There is very sparse data on LSD in hair samples (the “tests” that have been conducted on hair doused with LSD externally, not by way of internal ingestion). Researchers are even unsure whether the drug is stable and detectable in these samples.
10. Extracting tissue samples is another way to test (this has, apparently, and only been done in rats or recently deceased humans).
11. To summarize. LSD leaves the blood after about 24 hours. Current tests are not able to detect LSD or its byproducts in urine samples after 72 hours.
12. In closing, other drugs that are similar in structure may interfere with the detection of LSD, depending on the test — some are more accurate than others. For example, some tests have high false-positive rates, which means that they falsely detect LSD when it is not present.