On Tuesday, Feb. 13th, 2018 the agency said the new computer model [which has been disparaged by some prominent scientists] it developed shows that kratom contains opioid compounds with potentially deadly side effects such as seizures and depressed breathing. The Drug Enforcement Administration is weighing whether to place kratom, which comes from a leafy Southeast Asian tree, in…
Study leader Rachel Thayer, of the Department of Psychology and Neuroscience at the University of Colorado Boulder, and colleagues recently reported their results in the journal Addiction … The team notes that any reduction in the size of white or gray matter or a loss in their integrity can lead to impairments in brain functioning. Scientists at the University…
Just one of the FDA’s cases appears to involve the presence of kratom alone, though the report includes no information on the death apart from the subject’s age and ethnicity. The report shows the individual tested positive for high levels of mitragynine [which is a industrialized and processed extract of the Kratom plant, distinct from…
So as an industrial medicinal chemist, I have some problems with the way the FDA is making its case here. It’s true that computational models of drug function have become more common, but “reliable” is a tricky word. If these things were truly reliable, to the point that you’d be comfortable setting government policy according…
From a physiological perspective, however, LSD is known to be non-toxic and medically safe when taken at standard dosages (50–200 μg). The scientific literature, along with recent media reports, have unfortunately implicated “LSD toxicity” in five cases of sudden death. On close examination, however, two of these fatalities were associated with ingestion of massive overdoses,…
*molecule of naloxone [Eugene] police are increasingly coming into contact with illicit drugs on patrol, including fentanyl…a synthetic opioid. Eugene Police have a new tool in their efforts to help addicts in crisis: the drug naloxone, which can reverse opioid overdoses. Besides using naloxone sprayers on [people who use drugs], officers can use them on…
…a substance called psilocybin. This is the principal psychedelic component in shrooms, responsible for their mind-bending, mood-altering properties. This study builds on an earlier experiment, which found that psilocybin can reduce blood flow in the amygdala, as well as symptoms of depression. At the time, researchers explained that the drug had produced an “after-glow” that…
The figures show the depth of the impact parental alcohol abuse can have on young people’s physical and mental health. The pressure they are exposed to can lead some of them to run away from home or to be excluded from school. Whilst parents seem to be self-medicating with alcohol to cope with their condition…
“I believe that psychedelics hold a potential to cure deep psychological wounds, and I believe that by investigating their neuropsychopharmacological mechanism, we can learn to understand this potential,” study author Leor Roseman, a PhD student at Imperial College London told PsyPost. A study has revealed that majority of patients taking mushrooms, seemed to have eased…
“I believe that psychedelics hold a potential to cure deep psychological wounds, and I believe that by investigating their neuropsychopharmacological mechanism, we can learn to understand this potential,” explained study author Leor Roseman, a PhD student at Imperial College London. “It is important to emphasize that psilocybin-assisted therapy is a model in which the patient…
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