Science

How MDMA resensitizes the brain

…in mice, MDMA can reopen the critical period for social learning after it should have closed permanently. In 2019, neuroscientist Gül Dölen’s laboratory at Johns Hopkins University in Baltimore, Maryland, found that the psychedelic drug MDMA resensitizes the brains of adult mice so they can learn from their social environment in a way that’s normally…

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Decreases in state and trait anxiety post-psilocybin: a naturalistic, observational study…

Anxiety disorders are the most common type of psychiatric disorders among Western countries. Evidence-based treatment modalities including pharmacological and cognitive-behavioral therapy result in deficient treatment responses… the raw data supporting the conclusions of this article will be made available by the authors, without undue reservation… the authors declare that the research was conducted in the…

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Psychedelic drugs… brain’s dynamic landscape

…LSD and psilocybin activate serotonin receptors on brain cells in a way that reduces the energy needed for the brain to switch between different activity states, according to a study led by Weill Cornell Medicine researchers… “Serotonin 2a receptors have a spatial distribution in the brain that appears to be optimized for lowering these state…

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…social… with psychedelics…

…we are planning a study right now using a citizen-scientist approach, says Sonja Lyubomirsky, a psychologist at UC Riverside. We’re going to ask people to get together with a friend and have a deep conversation. We’re going to have a placebo, which may be either a lower dose of the drug, or it could be…

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…fentanyl overdoses…

Just a quarter of a milligram – 0.25 milligrams – can kill you. For a sense of just how little that is, a typical baby aspirin tablet is 81 mg. If you cut that tablet into 324 pieces, one of those pieces would be equal to a quarter-milligram. In the year ending in April 2019,…

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…Awareness… the implementation of medical cannabis and psychedelics… adjunct to standard therapy… advanced metastatic…

Published in the Journal, Drug Science, Policy and Law, [with authors Rayyan Zafar and David Nutt (who performed the first MRI of a human brain under the influence of LSD)], from Imperial College London, Centre for Psychedelic Research and Neuropsychopharmacology, UK: this case highlights the plausible therapeutic role of such plant-based medicines in oncology treatment…

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Psychedelic… research…

“I have a tremendous amount of respect for the research but it’s a completely sanitized, you know, sterilized subject pool. There’s all kinds of exclusion criteria and so it’s interesting, it gets a little bit more murky when you start to say well we’re going to study alcohol use disorder with co-morbid depression, right, so…

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…forage… grow…

For many mycophiles, psychonauts, and avid foragers, the start of shroom season is the highlight of the year… unlike cannabis grown from seed, hundreds, if not thousands, of unique subspecies can result from a single multi-spore inoculation. …magic mushrooms can be found on every continent except Antarctica. In the United States, psychedelic shrooms can be…

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Is marijuana a psychedelic?

The first is more scientific. Simply put, you decide whether a compound is “psychedelic” by seeing which brain receptors the molecule binds with. If a drug binds with specific serotonin receptors in the brain, the 5-HT2A receptors, it is considered a psychedelic. If it does not, then it is not a psychedelic. So, based on this…

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