…he’d made enough money to open the physical shop. His nervous landlord insisted on several months’ rent upfront. Out front, there’s a sign saying “Wir Verkaufen LSD” (we sell LSD)… …a new package of supplies has arrived, and there’s a constant stream of customers… The majority say they take the drug for fun, although some…
Brain-derived neurotrophic factor (BDNF) regulates neuronal development and survival and triggers adaptive neuroplasticity… animal studies have reported that acute and chronic administration of various psychedelic compounds, including LSD, psilocybin, DMT, and other ayahuasca-derived alkaloids, can increase BDNF production and neurogenesis (the formation of new neurons). Importantly, threats to our well-being such as stress, ageing and…
Perhaps the most intriguing finding in the study is the observation that the analgesic effect seen in the 20-µg LSD group is comparable to what prior studies have seen with in the same cold water pain test for opioids such as oxycodone and morphine. The researchers described the results of the study as “remarkable”, with…
[In the 1950’s and 60’s] psychedelics were of little interest to pharmaceutical companies as the intervention seemed to treat illness, rather than alleviate symptoms. Consequently, the financial imperatives were lacking; fully recovered patients would not require continued medication… Sandoz was reluctant to share such proprietary and patented data (Bonson, 2018). When required by the FDA, the company…
As long as he worked in the company [Sandoz], he was quite a conservative man, keeping his distance from the [so-called] counterculture, but the older he became, the more open he was to LSD use that went beyond therapy. …one of the most important things about LSD is that it can reconnect people with the living…
LSD is unstable, and the liver breaks it down rapidly. The time that LSD is detectable in the tissues is restrictive, so doctors need to analyze the samples quickly. *this article is a generalization, and not intended to replace the original source article. please view the original source article for full and detailed description, including…
Single “microdoses” of LSD produced orderly dose-related subjective effects in healthy volunteers. Numerous anecdotal reports suggest that repeated use of very low doses of lysergic acid diethylamide (LSD), known as “microdosing,” improves mood and cognitive function. These effects are consistent both with the known actions of LSD on serotonin receptors, and with limited evidence that…
“We just solved the same equation, for the harmonic patterns, on the human connectome instead of other geometrical shapes, like metal plates or spheres where it has been applied before,” Atasoy explains. “Then, when we take the fMRI data, instead of looking at where we see higher activity versus lower activity, we can ask the…
Whether or not you’ve tried LSD before, you have heard about bad trips. For [those] looking to take LSD while avoiding these nightmarish experiences, self-examination is your best bet … To avoid being overwhelmed… recommends that if [someone] is going to take LSD they should always do so with a group of close, supportive friends…
So how do psychedelics work to help patients? The experience can change a patient’s world view, and give an addict the will and the desire to break their addiction, or someone with a terminal illness the strength to face up to death. It’s a matter of neuroscience, says [Michael] Pollan. It’s possible, he says, that…
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