Increasing evidence suggests psilocybin may promote neuroplasticity, contributing to its antidepressant effects. In some people, postmortem studies indicate, depression may be related to disrupted adult hippocampal neurogenesis (AHN)—the birth and growth of new neurons in the hippocampus. This mechanism is important for regulating mood and maintaining spatial learning and memory throughout life, and it is critical for brain plasticity……
Like cannabis, psychedelic substances have been used across the globe for many purposes. And, like cannabis, psychedelics are relatively safe and have a low chance of dependence. And again, like cannabis they are not without risks, and there are steps that consumers can take to reduce the chance of harm. With cannabis buds, it is…
On June 8, 2023, court documents show, police busted a psilocybin grow house and major interstate mushroom-and-weed distribution operation in a 5,000-square-foot mansion bordering a Northeast Portland country club. …$1.3 million home on the border of the Columbia Edgewater Country Club, which features panoramic views of the golf course, a “unique triple barrel-vaulted ceiling” and…
The paper titled “Psychedelics and Psychological Strengths” discusses findings from three studies conducted through online surveys from a total of 3,157 participants. The researchers used controls for demographic variables, subjects’ use of other psychoactive drugs, and their beliefs about the potential benefits of psychedelic substances. The findings revealed that classical psychedelic users have “greater psychological…
Colorado voted to legalize psilocybin in 2022 [including state-wide home cultivation] and Oregon was the first state to allow adults to use [it] after a successful ballot measure passed in 2020. James Davis [who now runs Bay Staters for Natural Medicine] said legalization in Massachusetts would reduce the stigma that surrounds research scholars from studying…
…psychedelics spurred new growth in both baby and mature neurons. But the mind-bending substances were 1,000 times more efficient than Prozac at grabbing onto a key molecular hub, TrkB. With just a single dose, the drugs elevated mood in mice under chronic stress and reduced a previously-established fear. Psychedelics produce fast and persistent antidepressant effects…
“We disproved our initial hypothesis that psychedelic states (here with psilocybin) produce higher complexity,” Ort explained. “Unlike the observed reduction of complexity during dreamless sleep, anesthesia or minimally conscious states, the psychedelic state has the same quantitative complexity as in normal waking – even though the quality of the conscious experience has massively changed.” Ort…
After self-administering a color blindness test, known as the Ishihara Test, the subject took five grams of dried mushrooms, which is considered a relatively high dose of psilocybin. He then took the Ishihara Test periodically over the next four months. This test is composed of a series of flashcards that each feature a number made…
Oregon leads a new era of psilocybin… …first encountered psilocybin like many people have: in her youth. Original Article (Bend Bulletin):Oregon’s first licensed psilocybin facilitators want to change the worldArtwork Fair Use: Public domain
When Denver journalist Chris Walker contacted appointees to inquire about their backgrounds, he learned the governor’s office had prohibited them from speaking with the press or the public… gag order… when Polis announced his board appointments on January 27 [2023], local activists saw few names they recognized. No one from the Nowak Society or Natural…
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