Single “microdoses” of LSD produced orderly dose-related subjective effects in healthy volunteers. Numerous anecdotal reports suggest that repeated use of very low doses of lysergic acid diethylamide (LSD), known as “microdosing,” improves mood and cognitive function. These effects are consistent both with the known actions of LSD on serotonin receptors, and with limited evidence that…
“We just solved the same equation, for the harmonic patterns, on the human connectome instead of other geometrical shapes, like metal plates or spheres where it has been applied before,” Atasoy explains. “Then, when we take the fMRI data, instead of looking at where we see higher activity versus lower activity, we can ask the…
CBD and… [psilocybin] act at 5-HT2A, the psychedelic receptor, in different ways, resulting in markedly different effects. Whereas CBD has little binding affinity for the classical cannabinoid receptors, CB1 and CB2, several serotonin receptor subtypes are key docking sites for CBD, [including the 5-HT2A]. Original Article (Project CBD):CBD and the psychedelic receptorArtwork Fair Use: DrLee
Electric cars and power tools could harness this hemp technology, the US researchers say. The waste fibres from hemp crops can be transformed into high-performance energy storage devices, scientists say. They “cooked” cannabis bark into carbon nanosheets and built supercapacitors “on a par with or better than graphene” – the industry gold standard. Original Article…
Bechtold was expecting to find a link between teen marijuana use and a variety of later symptoms. But the study found that both physical ailments (such as cancer, asthma and respiratory problems) and mental ailments (such as lifetime depression and anxiety), were equally likely for non-marijuana users and frequent smokers … the results were published…
This doesn’t mean that antidepressants that affect levels of serotonin definitively don’t work—it simply means that we don’t know if they’re affecting the root cause of depression. A drug’s effect on serotonin could be a relatively inconsequential side effect, rather than the crucial treatment. A conglomeration of factors, beginning in the 1960s but having the…
Baeocystin was first isolated by Leung and Paul in 1968 from the mushroom Psilocybe baeocystis (hence the name). Other researchers later isolated it from Psilocybe semilanceata, Panaeolus renenosus, Panaeolus subbalteatus, and Copelandia chlorocystis. Jochen Gartz refers to a report that “10 mg of baeocystin were found to be about as psychoactive as a similar amount of psilocybin.” Although the presence…
Consider these facts about phenethylamine … [Love-related chemical. Carbon = black hydrogen = white nitrogen = blue] … [The brain’s best known love chemical is phenylethylamine, or PEA. It is a naturally occurring amphetamine. “Love is a drug,” says Helen Fisher, an anthropologist at Rutgers University and author of Anatomy of Love.] It acts as…
Experts warn that it isn’t necessarily a “miracle cure” – it can come with side-effects and nothing is known about the risks of using it long term. [Afterall], the [patient outcome] results were decidedly mixed and some scientists have pointed out that the FDA relaxed its usual rules for accepting drugs, in order to let…
Researchers from the University of Oregon dosed mice with a powerful psychedelic drug and with unprecedented detail zoomed in on how the animal’s brains subsequently generated visual hallucinations. DOI is often used in research conditions as it is not currently a schedule one drug in the United States, unlike its better known psychedelic counterparts. The…
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