Science

Psilocybin induces acute and persisting alterations in immune status and the stress response in healthy volunteers

January 10, 2023By

Patients characterized by stress-related disorders such as depression display elevated circulating concentrations of pro-inflammatory cytokines and a hyperactive HPA axis. Psychedelics are demonstrating promising results in treatment of such disorders… Psilocybin immediately reduced concentrations of the pro-inflammatory cytokine tumor necrosis factor-α (TNF-α), while other inflammatory markers (interleukin (IL)-1α, IL-1β, IL-6, and C-reactive protein (CRP)) remained…

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Politics

California bill builds on reforms that could herald the surprisingly fast collapse of psychedelic prohibition

January 10, 2023By

SB 58; Ash Kalra… is a principal co-author… co-authored by assembly members Buffy Wicks… Evan Low… Matt Haney… Alex Lee… Isaac Bryan… Lola Smallwood-Cuevas… Senator Wiener is a leader within a larger movement to end the so-called “War on Drugs and its failed and destructive policies.” He’s also advocated for opening “safe consumption sites” for…

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Politics

…collective… path… act

January 10, 2023By

…the idea that any of us are neutral is a fallacy. You can’t be neutral on a moving train. Bridges, for that matter, aren’t neutral either. Bridges hold tension, receiving charge and information from all sides, not to neutralize but to ensure a balanced exchange… just because people voted “no” doesn’t mean they are prohibitionists.…

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Politics

…allowing… uses… of psilocybin…

January 10, 2023By

Compared to the gradual collapse of marijuana prohibition, psychedelic policy seems to be shifting remarkably fast. While states began banning cannabis a century ago, culminating in the Marihuana Tax Act of 1937, prohibition of psychedelics was enacted in the late 1960s… [for example, in Virginia], proposing to make psilocybin, the hallucinogenic substance found in “magic…

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Politics

…confirmatory phase 3…

January 10, 2023By

MDMA will be either approved or rejected as a legal prescription medicine. …positive results from… a multi-site Phase 3 study of MDMA-assisted therapy for post-traumatic stress disorder (“PTSD”). The study met both the primary endpoint as measured by the change from baseline in Clinician-Administered PTSD Scale for DSM-5 (“CAPS-5”) and the key secondary endpoint of…

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Science

The rebirth of psychedelic…

January 10, 2023By

From what researchers have seen so far, however, there has not been compelling evidence that these drugs can work without the holistic process of preparation, “trip” and integration. …many researchers are excited to get their hands on a new set of tools to help treat mental disorders that have long resisted conventional forms of treatment……

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Psychology

Oregon’s… psilocybin… [services…]… [Measure 111 – SJR 12]

January 3, 2023By

The Oregon Psilocybin Services Manager… at the Oregon Health Authority is Angela Allbee… asked what kinds of complaints she’s hearing, Albee said she couldn’t discuss specifics but that the commonest complaint to the agency is “I think my neighbor is growing magic mushrooms.” State… has issued 200-plus licenses… [out-of-state] psychedelic tourists are checking out Portland,…

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Politics

Varieties… [psilocybin cubensis]

January 3, 2023By

Oregon’s education and licensing requirements illustrate the potential for regulatory drift. Like adult use cannabis, Measure 109’s supported adult use model allows people to access psilocybin for any reason, such as personal or spiritual growth and the promotion of physical and mental wellness. However, unlike adult use cannabis, Measure 109’s supported adult use model requires…

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Politics

Legal use [of psilocybin cubensis] mushrooms begins in Oregon

January 3, 2023By

…the long-awaited moment of legalized psychedelics… finally arrived. Officials… said the biggest tensions were over affordability, since psilocybin will not be covered by insurance… a single session is likely to cost hundreds, if not thousands of dollars. On Jan. 1 [2023], Oregon became the first state in the nation to legalize the adult use of…

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Politics

Oregon… [M109 psilocybin cubensis]… rules…

January 3, 2023By

…some… urged the Oregon Health Authority (OHA) to require clients to agree to share data as a condition of receiving psilocybin. In its final version of the client bill of rights, the OHA deleted the limitation to personal information and reintroduced the right “to refuse to release any information to third parties”, restoring clients’ ability to control how their information is…

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