Notably, [alcohol is] prohibited or discouraged in certain social, religious, and cultural groups for this reason. While both substances alter consciousness and can affect mood and perception, they do so through very different mechanisms and carry different risks, experiential effects, and legal statuses. Although alcohol is culturally ingrained in many social contexts, its high potential…
“Recent neuroimaging studies combined with small sample interventions with classic psychedelic agents,” authors wrote, “may point towards a possible means of improving the treatment of chronic pain on a mechanistic and experiential level.” Numerous small trials of… psilocybin for chronic pain have already shown a good safety profile, with minimal physical dependence, withdrawal syndrome, or…
“12 patients met both response and remission criteria” at the end of a 12-week study period, the trial found, meaning that measures of the diagnosis had dropped by more than half and fell below a minimum threshold. Results… published by the American Medical Association “suggest efficacy and safety” of psilocybin-assisted psychotherapy for treatment of bipolar…
According to a study published… in the journal Current Biology, commercially cultivated varieties (or cultivars) of psilocybin mushrooms like Psilocybe cubensis aren’t as genetically diverse as their naturally grown counterparts and show signs of inbreeding. This finding was based on a genomic analysis of 38 different Psilocybe cubensis found growing in the Australian wild compared…
…researchers have uncovered a potentially promising connection between the use of psychedelic mushrooms and a reduction in psychological distress, particularly among individuals who have experienced adverse childhood experiences. The study was published in the Journal of Psychoactive Drugs. …study aimed to explore the relationship between psilocybin use and psychological distress, with a specific focus on individuals…
The conversation about how much to take is increasingly broad reaching. For a long time, Terence McKenna’s philosophy of 5 dried grams in silent darkness ruled the day. In the early 2000s, 3.5 grams was considered a dose. More recently, the advised introductory recreational dose was closer to 2.5 grams, and the museum dose around…
A recently published study, which was conducted during the… pandemic, suggests that individuals who have used psychedelic substances experience lower psychological distress, improved well-being, and enhanced post-traumatic growth. The new findings appear in the journal Scientific Reports. …pandemic presented an unusual opportunity to investigate the relationship between hallucinogenic drug use and mental health. With much of…
Psilocybin has become a household name in the last decade. It’s been decriminalized in two states – Colorado (five natural psychedelic compounds: DMT, ibogaine, mescaline, psilocybin and psilocin) and Oregon… [psilocybin which converts to] psilocin [in the body] not only penetrates the cell membrane and binds to these very specific receptors, it binds stronger than…
…why numerous… reports laud the positive wellbeing effects of psychedelic mushrooms. An increased resilience to stress and a reduction in compulsive behaviors among the rodent subjects. Moreover, enhanced connectivity to the brain’s thalamus, implicated in decision-making and concern filtration… In the recent study published in Nature – Molecular Psychiatry, Associate Professor Mikael Palner and PhD…
A new study published in the European Journal of Pain last month [July 2023] found that both macro and micro doses of classic psychedelics — LSD, psilocybin, DMT, mescaline — led to better pain relief compared to conventional medication in volunteers surveyed. “Participants reported that full doses seem to achieve better perceived results in pain relief than…
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