The only reference to psilocybin on the Food and Drug Administration’s website appears in the agency’s Bad Bug Book: Handbook of Foodborne Pathogenic Microorganisms and Natural Toxins, where the psychedelic compound is described as a “neurotoxin” found in mushrooms. The FDA’s dueling portrayals of psilocybin as a scary fungal neurotoxin and a promising treatment for depression…
This present research focuses on the effect of LSD on alcohol intake in a two-bottle choice drinking paradigm in C57BL/6J mice, an inbred alcohol-preferring strain (Melo et al., 1996). In the group treated with 50 μg/kg LSD, mean daily ethanol consumption was 13.62 ± 3.02 g/kg/day compared to 16.60 ± 3.52 g/kg/day (mean ± SD)…
*mushroom picture not for identification purposes So if the called-for reclassification does indeed take place, psilocybin would go from being treated like an outlawed narcotic to – basically – a prescription sleeping pill. “We should be clear that psilocybin is not without risks of harm, which are greater in recreational than medical settings,” Johnson says.…
There is still a lot of social stigma and fear surrounding psychedelic drugs. But properly-conducted clinical trials are rapidly replacing assumptions with solid scientific knowledge, the researchers say.“This area of regulatory science has the potential to facilitate innovative therapeutic breakthroughs by replacing fear and misinformation with scientifically based conclusions and facts,” they write. Based on…
In a paper published… in the journal Cell Reports, a team of researchers showed evidence that psychedelic drugs can induce structural changes in nerve cells — a trait called neuroplasticity — that could, in turn, help repair brain dysfunction in people with mood and anxiety disorders. “The structure of neurons affects their function, and in the case of…
The state wasn’t going to allow outdoor farming until… people successfully convinced the regulators to allow sun-grown weed. It’s also the more environmentally friendly choice. Outdoor farming will always use less energy. Indoor farmers need a lot of power to run their lights and fans. Just like the grape vines for winemaking, pot plants absorb…
In this new study, a large group of Brazilian scientists carried out the first randomized placebo-controlled trial with ayahuasca, treating 29 patients with treatment-resistant depression. Half of the patients were treated with ayahuasca, and the other half with placebo. “We observed a significant placebo effect, but the effects of ayahuasca were superior, and lasted longer,”…
Its scientific advisory board includes Tom Insel, the former director of the National Institutes of Mental Health.While most of the research is being led by universities and non-profit research institutions, Compass, a for-profit company founded in 2016, sees itself as helping to fill in the gaps … For the trial, which is set to begin within…
About 500 brain experts from 29 countries are attending the group’s annual meeting, CNS 2018 (27th Annual Computational Neuroscience Meeting), which has been jointly organized by the Allen Institute for Brain Science and the University of Washington. [An] experiment took advantage of functional MRI brain scans to document how psilocybin changed brain activity. The psychedelic drug reduced the activity of…
Greg Boyce, a member of Kasson’s team, looked at all the chemicals found in the white fungal plugs of the various cicadas. And to his shock, he found that the banger-wings were loaded with psilocybin—the potent hallucinogen found in magic mushrooms. “At first, I thought: There’s absolutely no way,” he says. “It seemed impossible.” After…
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