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A psychedelics expert says magic mushrooms will be approved for depression by 2027 — here’s why

“I’m absolutely sure that, within ten years, psilocybin will be an accepted treatment for depression,” David Nutt, the director of the neuropsychopharmacology unit in the division of brain sciences at Imperial College London told me last month.”

One key characteristic of depression is overly strengthened connections in brain circuits in certain regions of the brain — particularly those involved in concentration, mood, conscious thought, and the sense of self. This may be part of the reason that electroconvulsive therapy, which involves placing electrodes on the temples and delivering a small electrical current, can help some severely depressed people — it tamps down on some of this traffic. “In the depressed brain, in the addicted brain, in the obsessed brain, it gets locked into a pattern of thinking or processing that’s driven by the frontal, the control center, and they cannot un-depress themselves,” Nutt told me.
Nutt is one of the pioneering researchers in the field of studying how psychedelics might be used to treat mental illness. He said that in depressed people, these overly trafficked circuits — think West Los Angeles at rush hour — can lead to persistent negative thoughts. Feelings of self-criticism can get obsessive and overwhelming. So to free someone with depression from those types of thoughts, traffic would need to be diverted from some of these congested ruts and, even better, redirected to emptier highways. That’s precisely what psychedelics appear to do.

Original Article (Business Insider):
A psychedelics expert says magic mushrooms will be approved for depression by 2027 — here’s why
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